Bagenal FS, Easton DF, Harris E, Chilvers CE, McElwain TJ. Survival of patients with breast cancer attending Bristol Cancer Help Centre. Lancet 1990;336:606-610.
Diet, nutrition and lifestyle changes:
Brittenden J, Heyes SD, Miller I, Sarkar TK, Hutcheon AW, Needham G, et al. Dietary supplementation with L-arginine in patients with breast cancer (>4 cm) receiving multimodality treatment: report of a feasibility study. Br.J.Cancer 1994; 69:918-921.
Hoffer A, Pauling L. Hardin Jones. Biostatistical analysis of mortality data for a second set of cohorts of cancer patients with a large fraction surviving at the termination of the study and a comparison of survival times of cancer patients receiving large regular doses of vitamin C and other nutrients with similar patients not receiving these doses. J.Orthomol.Med. 1993;8:(3)157-167.
Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in 'high risk' patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol.Aspects Med. 1994;15:(Supplement)s231-s240
Recchia F, Rhea S, Pompili P, Casucci D, Rea MJ, Rizzo F, et al. Beta-interferon, retinoids and tamoxifen as maintenance therapy in metastatic breast cancer : a pilot study. Clin.Ter. 1995;146:603-610.
Recchia F, Sica G, De filippis S, Discepoli S, Rea S, Torchio P, et al. Interferon-beta, retinoids, and tamoxifen in the treatment of metastatic breast cancer: a phase II study. J.Interferon Cytokine Res. 1995;15:605-610.
Herbal medicine:
Kovacs E, Hajto T, Hostanska K. Improvement of DNA repair in lymphocytes of breast cancer patients treated with Viscum album extract (Iscador). Eur.J.Cancer 1991; 27:1672-1676.
Mind/body control:
Gellert GA, Maxwell RM, Siegel BS. Survival of breast cancer patients receiving adjunctive psychosocial support therapy: a 10-year follow-up study. J.Clin.Oncol. 1993; 11:(1)66-69.
Morgenstern H, Gellert GA, Walter SD, Ostfeld AM, Siegel BS. The impact of a psychosocial support program on survival with breast cancer: the importance of selection bias in program evaluation. J.Chron.Dis. 1984;37:273-282.
Newton BW. The use of hypnosis in the treatment of cancer patients. Am.J.Clin.Hypn. 1983;25:104-113.
Simonton OC, Matthews-Simonton S, Sparks TF. Psychological intervention in the treatment of cancer. Psychosomatics 1980;21:226-231.
Spiegel D, Bloom JR, Kraemer HC, Gottheil E. Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet 1989; 2:888-891.
Pharmacological and biological treatments:
Burzynski SR, Kubove E, Burzynski B. Phase I clinical studies of antineoplaston A5 injections. Drugs Exp.Clin.Res. 1987;XIII:37-43.
Lissoni P, Barni S, Ardizzoia A, Tancini G, Conti A, Maestroni G. A randomized study with the pineal hormone melatonin versus supportive care alone in patients with brain metastases due to solid neoplasms. Cancer 1994; 73:699-701.
Lissoni P, Barni S, Cattaneo G, Tancini G, Esposti G, Esposti D, et al. Clinical results with the pineal hormone melatonin in advanced cancer resistant to standard antitumor therapies. Oncology (Switzerland) 1991;48:448-450.
Lissoni P, Barni S, Meregalli S, Fossati V, Cazzaniga M, Esposti D, et al. Modulation of cancer endocrine therapy by melatonin: a phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progressing under tamoxifen alone. Br.J.Cancer 1995; 71:854-856.
Lissoni P, Barni S, Tancini G, Ardizzoia A, Ricci G, Aldeghi R, et al. A randomised study with subcutaneous low-dose interleukin 2 alone vs interleukin 2 plus the pineal neurohormone melatonin in advanced solid neoplasms other than renal cancer and melanoma. Br.J.Cancer 1994;69:196-199.
Moertel CG, Ames MM, Kovach JS, Moyer TM, Rubin J, Tinker JH. A pharmacologic and toxicological study of amygdalin. JAMA 1981;245:591-594.
Moertel CG, Fleming TR, Rubin J, Kvols LK, Sarna G, Koch R, et al. A clinical trial of amygdalin (Laetrile) in the treatment of human cancer. N.Engl.J.Med. 1982;306:201-206.
Studies of the Effect of Unconventional Therapies on Discomfort Due to Breast Cancer
Alternative programs of medical practice:
Clover A, Last P, Fisher RA. Complementary anticancer therapy: a pilot study of patients, therapy and quality of life. Compl.Therap.Med. 1995;3:129-133.
Energy therapies:
Filshie J, Redman D. Acupuncture and malignant pain problems. Eur.J.Surg.Oncol. 1985; 11:389-394.
Herbal medicine:
Kuttan R, Sudheeran PC, Josph CD. Turmeric and curcumin as topical agents in cancer therapy. Tumori 1987;73:29-31.
Manual healing:
Sims S. Slow stroke back massage for cancer patients. Nurs.Times 1986;82:47-50.
Mind/body control:
Arathuzik D. Effects of cognitive-behavioral strategies on pain in cancer patients. Cancer Nurs. 1994;7:207-214.
Beck SL. The therapeutic use of music for cancer-related pain. Oncol.Nurs.Forum 1991; 18:1327-1337.
Davis H4. Effects of biofeedback and cognitive therapy on stress in patients with breast cancer. Psychol.Rep. 1986;59:967-974.
Spiegel D, Bloom JR. Group therapy and hypnosis reduce metastatic breast carcinoma pain. Psychosom.Med. 1983; 45:333-339.
Pharmacological and biological treatments:
Chlebowski RT, Bulcavage L, Grosvenor M, Tsunokai R, Block JB, Heber D, et al. Hydrazine sulfate in cancer patients with weight loss. Cancer 1987;59:406-410.
Lissoni P, Barni S, Brivio F, Rossini F, Fumagalli L, Ardizzoia A, et al. A biological study on the efficacy of low-dose subcutaneous interleukin-2 plus melatonin in the treatment of cancer-related thrombocytopenia. Oncology 1995;52:360-362.
Lissoni P, Paolorossi G, Tancini S, Barni S, Adrizzoia F, Brivio F, et al. Is there a role for melatonin in the treatment of neoplastic cachexia? Eur.J.Cancer 1996;8:1340-1343.
Studies of the Effect of Unconventional Therapies on Immune Function in Breast Cancer Patients
Diet, nutrition and lifestyle change:
Black MM, Zachrau RE, Dion AS, Katz M. Stimulation of prognostically favorable cell-mediated immunity of breast cancer patients by high dose vitamin A and vitamin E. Vitam.Nutr.Cancer 1984;134-146.
Brittenden J, Park GM, Heys SD, Ross C, Ashby J, Ah-See AK, et al. L-arginine stimulates host defenses in patients with breast cancer. Surgery 1994;115:205-212.
Garritson BK, Nikaein A, Peters GN, Gorman MA, King CC, Liepa GU. Effect of major dietary modifications on the immune system in patients with breast cancer: a pilot study. Cancer Pract. 1995;3:239-246.
Energy therapies:
Chengjiang H, Kehui G, Qunzhu X, Youyu Y, Huanwei L, Fusheng G. Effects of microwave acupuncture on the immunological function of cancer patients. J.Tradit.Chin.Med. 1987;7:9-11.
Herbal medicine:
Beuth J, Ko HL, Gabius HJ, Burrichter H, Oette K, Pulverer G. Behavior of lymphocyte subsets and expression of activation markers in response to immunotherapy with galactoside-specific lectin from mistletoe in breast cancer patients. Clin.Investig. 1992; 70:658-661.
Hajto T. Immunomodulatory effects of iscador: a Viscum album preparation. Oncology 1986;43 Suppl 1:51-65.
Hajto T, Lanzrein C. Natural killer and antibody-dependent cell-mediated cytotoxicity activities and large granular lymphocyte frequencies in Viscum album-treated breast cancer patients. Oncology 1986;43:93-97.
Heiny B-M, Beuth J. Mistletoe extract standardized for the galactoside - specific lectin (ML-1) induces beta-endorphin release and immunopotentiation in breast cancer patients. Anticancer Res. 1994;14:1339-1342.
Hou J, Liu S, Ma Z, Lang X, Wang J, Liang Z. Effects of gynostemma pentaphyllum makino on the immunological function of cancer patients. J.Tradit.Chin.Med. 1991; 11:47-52.
Li Y, Yu G. A comparative clinical study on prevention and treatment with selected chronomedication of leukopenia induced by chemotherapy. J.Tradit.Chin.Med. 1993; 13:257-261.
Mind/body control:
Gruber BL, Hersh SP, Hall NR, Waletzky LR, Kunz JF, Carpenter JK, et al. Immunological responses of breast cancer patients to behavioral interventions. Biofeedback Self Regul. 1993;18:1-22.
Richardson MA, Post-White J, Grimm EA, Moye LA, Singletary SE, Justice B. Coping, life attitudes, and immune responses to imagery and group support after breast cancer treatment. Altern.Ther.Health Med. 1997;3:(5)62-70.
Studies of the Effect of Unconventional Therapies on Side-Effects of Conventional Treatments
Diet, nutrition and lifestyle change:
Loprinzi CL, Athmann LM, Kardinal CG, O'Fallon JR, See JA, Bruce BK, et al. Randomized trial of dietician counseling to try to prevent weight gain associated with breast cancer adjuvant chemotherapy. Oncology 1996;53:228-232.
Myers C, Bonow R, Palmeri S, Jenkins J, Corden B, Locker G, et al. A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine. Semin.Oncol. 1983;10:53-55.
Energy therapies:
Dundee JW, Ghaly RG, Fitzpatrick KTJ, Abram WP, Lynch GA. Acupuncture prophylaxis of cancer chemotherapy-induced sickness. J.R.Soc.Med. 1989;82:269-271.
Dundee JW, Yang J. Prolongation of the antiemetic action of P6 acupuncture by acupressure in patients having cancer chemotherapy. J.R.Soc.Med. 1990;83:360-362.
Lundeberg T, Kjartansson J, Samuelsson U. Effect of electrical nerve stimulation on healing of ischaemic skin flaps. Lancet 1988;2:712-714.
Herbal medicine:
Maiche AG, Grohn P, Maki-Hokkonen H. Effect of chamomile cream and almond ointment on acute radiation skin reaction. Acta Oncol. 1991;30:395-396.
Manual healing:
Hornsby R. The use of compression to treat lymphoedema. Prof.Nurse 1995;11:127-128.
Zanolla R, Monzeglio C, Balzarini A, Martino G. Evaluation of the results of three different methods of postmastectomy lymphedema treatment. J.Surg.Oncol. 1984; 26:210-213.
Pharmacological and biological treatments:
Lissoni P, Tancini G, Barni S, Paolorossi F, Ardizzoia A, Conti A, et al. Treatment of cancer chemotherapy-induced toxicity with the pineal hormone melatonin. Support.Care Cancer 1997;5:(2)126-129.
