The Rosenthal Center for Complementary and Alternative Medicine

presents

Nikolaos Scarmeas, M.D.

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain

Columbia University

Mediterranean Diet and

Alzheimer’s Disease

Wednesday November 8, 2006

12:00 PM to 1:00 PM*

Merritt Conference Room
P&S 3-418, 630 W. 168th Street [next to Student Affairs Office]
 
 
*You are welcome to bring lunch

Nikolaos Scarmeas, M.D. is Assistant Professor of Clinical Neurology at the Taub Institute, Columbia University. Using epidemiological and brain imaging methods, he investigates the effect of cognitive reserve on coping with brain damage caused by AD. He also studies how cognitive, behavioral, genetic and imaging characteristics of patients with AD contribute to clinical heterogeneity and predict subsequent disease course, including cognitive-functional decline. 
 
Diet is believed to play a (positive and negative) role in AD, but evidence for individual dietary elements is conflicting. Recently, Dr. Scarmeas has begun to investigate the contribution of a composite dietary pattern, Mediterranean diet (MeDi), in AD risk.
 
 
 
 
 
 
Nikolaos Scarmeas, M.D. 
 

 
Selected Publications
 

Scarmeas N., Brandt J., Albert M., Devanand D., Marder K., Bell K., Ciappa A., Tycko B., Stern Y.: Association between APOE genotype and psychiatric symptoms in Alzheimer’s disease (AD). Neurology 2002; 58:1182-1188.

Scarmeas N., Zarahn E., Anderson K., Habeck C., Hilton J., Flynn J., Marder K., Bell K., Sackeim H., Van Heertum R., Moeller J., Stern Y.: Association of life activities with cerebral blood flow in Alzheimer’s disease: Implications for the cognitive reserve hypothesis. Archives of Neurology 2003; 60: 359-365.

Scarmeas N., Zarahn E., Anderson K.E., Hilton J., Flynn J., Van Heertum R., Sackeim H., Stern Y. Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects. Neuroimage 2003; 19: 1215-1227.

Scarmeas N., Zarahn E., Anderson K.E., Honig L.S., Park A., Hilton J., Flynn J., Sackeim H., Stern Y. Cognitive reserve mediated modulation of Positron Emission Tomography activations during memory tasks in Alzheimer’s disease. Archives of Neurology 2004; 61: 73-78.

Scarmeas N., Habeck C., Zarahn E., Anderson K., Park A., Hilton J., Pelton G., Tabert M., Honig L., Moeller J., Devanand D., Stern Y. Covariance PET patterns in early Alzheimer’s disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performance. Neuroimage 2004; 23(1): 35-45.

Scarmeas N., Anderson K., Hilton J., Park A., Habeck C., Flynn J., Tycko B., Stern Y. APOE dependent PET patterns of brain activation in Alzheimer’s disease. Neurology 2004; 63:913-915.

Scarmeas N., Habeck C., Anderson K., Hilton J., Devanand D., Pelton G., Tabert M., Flynn J., Park A., Ciappa A., Tycko B., Stern Y. Altered PET functional brain responses in cognitively intact elderly at risk for Alzheimer’s disease (carriers of the e4 allele). American Journal of Geriatric Psychiatry 2004; 12: 596-605.

Scarmeas N., Brandt J., Albert M., Hadjigeorgiou G.M., Papadimitriou A, Dubois B., Sarazin M., Devanand D., Honig L., Marder K., Bell K., Wegesin D., Blacker D., Stern Y. Hallucinations and delusions are associated with worse outcomes in Alzheimer’s disease (AD). Archives of Neurology 2005; 62: 1601-1608.

Scarmeas N., Albert S., Manly J., Stern Y. Education and rates of cognitive decline in incident Alzheimer’s disease. Journal of Neurology Neurosurgery and Psychiatry 2006; 77: 308-16.

Scarmeas N., Stern Y., Tang MX. Mayeux R., Luchsinger JA. Mediterranean diet and risk for Alzheimer's disease. Annals of Neurology 2006; 59: 912-921.

Scarmeas N, Stern Y, Mayeux R, Luchsinger JA. Mediterranean Diet, Alzheimer Disease, and Vascular Mediation. Arch Neurol. 2006 Oct 9; [Epub ahead of print]