The Rosenthal Center for Complementary and Alternative Medicine

 
and
 
The Department of Psychiatry
The NYS Psychiatric Institute and Columbia College of P&S

present

Helen Mayberg, M.D.

Paths To Recovery:

Putative neurocircuits mediating diverse treatments for major depression

Thursday September 21, 2006

4:00 PM to 5:00 PM

Location: New York State Psychiatric Institute, 1051 Riverside Drive, 1^st Floor Auditorium

(Enter Kolb Annex, 40 Haven Ave., turn rt., walk though atrium and across bridge over Riverside Dr. to new NYSPI, take elevator to 1st Fl.)

See over for speaker brief biography, selected publications
 
 
 
 
 
 

Dr. Mayberg’s online biography for conference, Investigating the Mind, Nov. 2005, Washington, DC, sponsored by the Mind and Life Institute. http://www.investigatingthemind.org/speakers.html#mayberg

HELEN S. MAYBERG is Professor of Psychiatry and Neurology at Emory University School of Medicine. She received her B.A. in Psychobiology from University of California, Los Angeles and the MD degree from the University of Southern California. Following an internship in Internal Medicine at the Los Angeles County-USC Medical Center, and a Residency in Neurology at the Neurological Institute, Columbia University College of Physicians and Surgeons in New York, she completed a post-doctoral fellowship in Nuclear Medicine at Johns Hopkins. Dr. Mayberg has held academic positions at Johns Hopkins, the University of Texas Health Sciences Center in San Antonio, and was the first Sandra Rotman Chair in Neuropsychiatry at the Rotman Research Institute and the University of Toronto.
The central theme of her research program is the use of functional neuroimaging methods to define critical neural pathways mediating normal and abnormal mood states in health and disease. Converging findings from a series of studies has led to a neural systems model of major depression. This model provides the foundation for ongoing experiments examining mechanisms of standard antidepressant treatments such as cognitive behavioral therapy and pharmacotherapy as well as development of novel surgical interventions for treatment resistant patients. Since her move in 2004 to Atlanta, these studies have been expanded to further address neurobiological markers predicting treatment response, relapse and resistance as well as depression vulnerability, with a goal towards developing imaging-based algorithms that will discriminate patient subgroups and optimize treatment selection in individual patients.

Neurobiology of placebo responding

Benedetti F, Mayberg HS, Wager TD, Stohler CS, Zubieta JK. Neurobiological mechanisms of the placebo effect. J Neurosci. 2005 Nov 9;25(45):10390-402. Review.

Mayberg HS, Silva JA, Brannan SK, Tekell JL, Mahurin RK, McGinnis S, Jerabek PA.The functional neuroanatomy of the placebo effect. Am J Psychiatry. 2002 May;159(5):728-37.

Affect regulation in depression

Tremblay LK, Naranjo CA, Graham SJ, Herrmann N, Mayberg HS, Hevenor S, Busto UE. Functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe. Arch Gen Psychiatry. 2005 Nov;62(11):1228-36.

Seminowicz DA, Mayberg HS, McIntosh AR, Goldapple K, Kennedy S, Segal Z, Rafi-Tari S.Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage. 2004 May;22(1):409-18.

Mayberg HS. Positron emission tomography imaging in depression: a neural systems perspective. Neuroimaging Clin N Am. 2003 Nov;13(4):805-15.

Mayberg HS. Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull. 2003;65:193-207. Review.

Mayberg HS. Modulating limbic-cortical circuits in depression: targets of antidepressant treatments.

Semin Clin Neuropsychiatry. 2002 Oct;7(4):255-68. Review.